Which type of inhibitor is considered a "suicide inhibitor"?

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Prepare for the UCF BCH4024 Medical Biochemistry Exam 1. Study with multiple choice questions and detailed explanations on various key topics. Boost your confidence and ensure you're ready for your exam!

The correct answer identifies a "suicide inhibitor" as a type of irreversible inhibitor. A suicide inhibitor works by binding to an enzyme in such a way that it is converted into an active form that permanently inactivates the enzyme. During this process, the inhibitor becomes covalently bonded to the enzyme, leading to a permanent loss of enzymatic activity. This contrasts with reversible inhibitors, which bind to enzymes non-covalently and can dissociate, allowing for restoration of enzyme function.

This irreversible action is a key feature of suicide inhibitors, as they effectively "commit suicide" by modifying the enzyme they target in a manner that prevents any further catalytic activity. Understanding this mechanism highlights the significance of enzyme regulation and the nuances of inhibitor types in biochemical pathways.